GitHub

Links to GitHub repositories for recent studies:

Male-biased mutation rates in rattlesnakes

We compared levels of autosomal and Z-linked sequence divergence between rattlesnake (Crotalus) species to infer a ratio of male-to-female mutation rate. We found evidence of a ~2-fold male-biased mutation rate, which has ramifications for rates of evolution in sex-linked genes in snakes.

Z-linked and autosomal genomic variation in barn swallows

Using a whole-genome resequencing dataset, we explored genetic diversity and differentiation across the genome between barn swallow (Hirundo rustica) subspecies. We compared variation on the Z chromosomes and autosomes to understand how different evolutionary processes have impacted sex-linked genetic diversity in this young species complex. We found evidence that low sex-linked diversity has been shaped by a combination of excess variance in male reproductive success, recent population bottlenecks, linked selection, and reduced gene flow on the Z chromosome.